【最新中稿作品】{ScnGdn} 异金属环、时空线型剪裁、电化学等-科技论文配图-医学动画-动画宣传片-三维机械动画制作-北京中科幻彩

研究介绍

Abstract （上下滑动查看）

In article number 2203680, Tian Jiang and co-workers demonstrate a novel reconfigurable metasurface supporting a symmetry-protected bound state in the continuum in the electromagnetic induced transparency window. With active media embedded in the proposed metasurface, spatiotemporal lineshape tailoring with resonance mode conversion and ultrafast amplitude switching is successfully achieved, which is appealing for next-generation flat photonic devices with high-compact, functionality-integrated, and fast-speed properties.

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Revealing the dynamic processes at the electrode–solution interface is imperative for understanding electrochemical phenomena. Most techniques have been developed to sense the electrode surface changes at the nanoscale, but provide limited information on potential-induced interfacial ion redistribution at the mesoscale. Herein, we present an in operando visualization method utilizing a microfabricated electrochemical cell combined with a laser scanning confocal microscope to observe high-resolution and fast-response interfacial processes. We report potential-induced formation and transformation of the Nernst diffusion layer, demonstrating that pulsed voltage dynamically perturbs the interface and promotes ion diffusion. This provides an additional insight into developing a dynamic manipulation method to control the electrochemical process. Our novel visualization method can easily be applied to monitor different ionic behaviors in electrochemical reactions at the mesoscale.

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With the excessive consumption of nonrenewable resources, the exploration of effective and durable materials is highly sought after in the field of sustainable energy conversion and storage system. In this aspect, metal-organic frameworks (MOFs) are a new class of crystalline porous organic-inorganic hybrid materials. MOFs have recently been gaining traction in energy-related fields. Owing to the coordination flexibility and multiple accessible oxidation states of vanadium ions or clusters, vanadium-MOFs (V-MOFs) possess unique structural characteristics and satisfactory electrochemical properties. Furthermore, V-MOFs-derived materials also exhibit superior electrical conductivity and stability when used as electrocatalysts and electrode materials. This review summarizes the research progress of V-MOFs (inclusive of pristine V-MOFs, V/M-MOFs, and POV-based MOFs) and their derivatives (vanadium oxides, carbon-coated vanadium oxide, vanadium phosphate, vanadate, and other vanadium doped nanomaterials) in electrochemical energy conversion (water splitting, oxygen reduction reaction) and energy storage (supercapacitor, rechargeable battery). Future possibilities and challenges for V-MOFs and their derivatives in terms of design and synthesis are discussed. Lastly, their applications in energy-related fields are also highlighted.

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Diabetic nephropathy (DN), a severe microvascular complication of diabetes mellitus (DM), results in high mortality due to the lack of effective interventions. The current study investigated the preventive effect of krill oil (KO) on DN using a type 2 DM mouse model induced by streptozotocin and high-fat diet for 24 weeks. The diabetic mice developed albuminuria, mesangial matrix accumulation, glomerular hypertrophy, and fibrosis formation, with an increase in renal proinflammatory, oxidative and profibrotic gene expression. KO significantly prevented these effects but did not improve hyperglycemia and glucose intolerance. In high-glucose-treated mesangial cells (MCs), KO preferably modulated TGF-β1 signaling as revealed by RNA-sequencing. In TGF-β1-treated MCs, KO abolished SMAD2/3 phosphorylation and nuclear translocation and activated Smad7 gene expression. The action of KO on the SMADs was confirmed in the diabetic kidneys. Therefore, KO may prevent DN predominantly by suppressing the TGF-β1 signaling pathway.

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Long-range olefin isomerization could lead to the remote functionalization of hydrocarbon chains, which is advantageous with regards to atom-, step-, and redox economy. However, present methodologies for long-range olefin isomerization are mainly focused on heteroatom directed remote olefin migration; studies using aryl groups as the directing group are limited. The limited examples either utilize aryl olefins with special substituted groups on a benzene ring, or use elaborately optimized ligands or co-catalysts to accelerate the isomerization. A more simple catalytic system for general aryl olefins, without the need for special ligands or co-catalysts, was to be developed. Herein, we report a Pd-catalyzed long-range olefin isomerization (up to 15 units) for general aryl olefins via a 1,2-hydrogen shift mechanism. This methodology provides a simple pathway to long-range olefin isomerization without the participation of special ligands or co-catalysts.

Abstract

The regulation of biological functions plays an important role in life processes. Molecular recognition usually manifests as the selectively combining process of two molecules, such as ligand and receptor, and subsequently performs a certain function. When the receptor binds to its ligand, a series of biochemical reactions will be initiated to activate or inhibit the downstream biological functions. The selective binding between ligand and receptor is based on non-covalent interactions, such as hydrogen-bond interactions and van der Waals forces. The interaction between ligand and receptor can be changed by molecular modification, and the downstream biochemical reaction, such as phosphorylation can thus be affected, thereby realizing the regulation of biological functions. The specific recognition of biomolecules in organisms is closely related to the occurrence and development of diseases. Precise molecular recognition has made outstanding achievements in biomolecular detection, drug therapy target discovery, and gene therapy. The regulation of biological functions through molecular recognition provides a theoretical basis for understanding the relationship between molecular structure and function at the molecular level, and will greatly promote the development and integration of chemical biology and life sciences. Herein, this themed column focuses on the burgeoning research in the regulation of biological functions through molecular recognition. The content includes the design and sensing strategies of molecular recognition, as well as the application of molecular recognition in the functional regulation of different life processes in organisms.

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